International Symposium on Neural Regeneration

The ISNR is a forum for the presentation and discussion of important research progress, insights and controversies important to advancing the understanding of injury responses and potential therapeutics targeting both peripheral nerve and central nervous system injuries.

The Craig H. Neilsen Foundation will again be the primary sponsor of the meeting as their funding is dedicated to supporting both programs and scientific research to improve the quality of life for those affected by and living with spinal cord injury. Mission Connect – A project of TIRR Foundation, Wings for Life, Shriner’s Hospital for Children and Rick Hansen Institute also have made a generous donations to help support this year’s meeting. An education grants from NIH-NINDS (R13) provide sadditional support.

For this year’s symposium, we will have two Keynote lecturers. Frank Bradke (DZNE, Bonn, Germany) will lead off the meeting and Kristian Franze (University of Cambridge) will anchor the meeting with a closing Keynote lecture.

Featured talks will be given by Michael McAlpine (Univ. of Minnesota), Yuh Nung Jan (UCSF), Kelly Monk (Vollum Inst, OHSU) and Linda Hsieh-Wilson (Caltech).

Following the format of preceding ISNR symposia, the program is divided into six sessions, including: 1) Axon regeneration-dynamics of dendritic or axon mRNA Translocation and protein synthesis, chaired by Os Steward; 2) Genetic dissection of axonal regeneration and degeneration, chaired by Michael Granato; 3) Young investigators improving spinal cord repair, chaired by John Gensel; 4) Exercise as a therapy for SCI: How to successfully move physical training from animal models to clinical implementation, chaired by Gordon Mitchell; 5) White matter plasticity and motor learning, chaired by Michele Basso; and 6) Matt Rasband (Baylor) will provide our Emerging Topics Lecture entitled: The functional organization of axons in neural repair and regeneration.

Click here to view the 2017 ISNR Program  for a complete list of all invited speakers and meeting agenda.

Posters and Abstracts

Two poster sessions have been scheduled: one on Tuesday, November 28th (3-5pm) and the other on Thursday, November 30th (2-4pm).

Selected Oral Presentations – Download the 2017 ISNR Data Blitz Agenda here

A complete list of the 2017 Abstracts can be found here

Eight selected abstracts will be presented as oral presentations (10 min/each) as part of a “Data Blitz” session immediately preceding the poster sessions on Tuesday (11/28) and Thursday (11/30).

Data Blitz – Tuesday November 28th, 2:00-3:00PM

2:00    Jessica Butts (jessie.butts@gladstone.ucsf.edu)

GENERATION OF V2A INTERNEURONS FROM HUMAN PLURIPOTENT STEM CELLS FOR SPINAL CORD INJURY REPAIR

2:10    Scott Dyck (dycksm@myumanitoba.ca)

MODULATION OF LAR AND PTPΣ FOSTERS A PRO-REGENERATIVE IMMUNE RESPONSE THAT PROMOTES OLIGODENDROGENESIS FOLLOWING SPINAL CORD INJURY

2:20    Alexandra Halevi (ahalevi@wustl.edu)

MODULATING PAIN BEHAVIOR WITH A PROXIMAL CRUSH INTERVENTION

2:30    Percy Algarate (percy.algarate@yale.edu)

CHRONIC IN VIVO IMAGING OF INTACT CORTICOSPINAL MOTOR NEURONS REVEALS FUNCTIONAL RE-ORGANIZATION AFTER PARTIAL SPINAL CORD INJURY

2:40    Brittany Charsar (brittany.charsar@jefferson.edu)

FOCAL OVEREXPRESSION OF BDNF PROMOTES TARGETED REINNERVATION OF PHRENIC MOTOR NEURONS AND RESTORATION OF DIAPHRAGMATIC RESPIRATORY FUNCTION AFTER CERVICAL SPINAL CORD INJURY

2:50    Matt Goodus (mgoodus@gmail.com)

ENHANCING HEPATIC INFLAMMATION BEFORE SCI CAUSES INCREASED LIVER AND SPINAL CORD PATHOLOGY

Data Blitz – Thursday, November 30th, 1:00-2:00PM

1:00    Christopher Ahuja (christopherahuja@gmail.com)

SMART NEURAL STEM CELLS TO DEGRADE SCAR AND OPTIMIZE REGENERATION AFTER TRAUMATIC SPINAL CORD INJURY

1:10    Marissa Ciesla (mciesla@ufl.edu)

IMPACT OF FOLATE ON RESPIRATORY RECOVERY AFTER CERVICAL SPINAL INJURY

1:20    Camila Marques de Freria (Camila.deFreria@osumc.edu)

SYSTEMIC LPS ELICITS NEUROPROTECTIVE MICROGLIA AND PROTECTS AGAINST ISCHEMIC SPINAL CORD INJURY

1:30    Lydia Hager (lydia.hager@uky.edu)

TOWARD PRECISION MEDICINE AFTER SCI: THE GENETIC INFLUENCE OF APOE ON RESPIRATORY MOTOR PLASTICITY

1:40    Dylan McCreedy (dylan.mccreedy@gmail.com)

DICLOFENAC REDUCES ACUTE OXIDATIVE STRESS AND IMPROVES LONG-TERM RECOVERY FOLLOWING SPINAL CORD INJURY

1:50    Tatiana Slepak (tslepak@med.miami.edu)

S6 Kinase 1 inhibition activates mTOR in Central Nervous System neurons promoting neurite outgrowth, axon sprouting and regeneration

Travel award winners:

Click here for a completed list of 2017 travel award winners.

Program Planning Committee for 2017

  • Phillip Popovich – The Ohio State University (Director; current SAB member)
  • Gordon Mitchell – Univeristy of Florida (current SAB member)
  • Ona Bloom – Hofstra North Shore-LIJ School of Medicine and The Feinstein Institute for Medical Research (current SAB member)
  • Elizabeth Bradbury – King’s College London (current SAB member)
  • Michael Bastiani – University of Utah (current SAB member)
  • Amy Moore– Washington University (current SAB member
  • Valeria Cavalli– Washington University (current SAB member)
  • Monica Perez– The Miami Project (current SAB member
  • David Magnuson-University of Louisville (current SAB member)
  • Jan Schwab-The Ohio State University (current SAB member)

Ex-officio representatives of co-sponsoring institutions were:

  • Naomi Kleitman – Craig H. Neilsen Foundation
  • Lyn Jakeman – NIH/NINDS (via Conference)

QUICK LINKS:

2017 Program