Scientific Program

The XIX ISNR

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Sunday

April 23, 2023

session I: welcome & Opening keynote

6:30 PM - WELCOME

6:45 PM OPENING KEYNOTE Tessa Gordon (UToronto/SickKids): Axonal regeneration and its clinical relevance

8:00 PM - DINNER AND WELCOME RECEPTION

*Posters: Please set up posters on Monday for display throughout the meeting.

** Post-it Forum: Want to learn more about a technique? Hiring trainees? Looking for a position? Having trouble with that cfos antibody? Just have something nice to say? Post it to the bulletin board with your name and contact info. If you get an answer, reach out and help! Check back frequently to see if you can pay it forward. From registration until the curtains close…

Monday

April 24, 2023

SESSION II: Ultimate Translation - From Preclinical Models to Human Clinical Trials

8:15 AM - TRIP Session Sponsored by the American Spinal Injury Association (ASIA):

CHAIRPERSON Edelle Field-Fote, PhD (Shepherd Center, Emory University)

8: 15 AM - Linda Jones, PhD Introduction to TRIP

8:20 AM - Edelle Field-Fote Essentials for Translation

8:30 AM - David Mack (Univ. Washington) Updates on the use of stem cells as therapeutic interventions to treat neuromuscular diseases, including Duchenne muscular dystrophy

8:55 AM - Eva Widerström-Noga (Miami Project to Cure Paralysis) Pain after SCI

9:20 AM - Linda Noble-Haeusslein (UT Austin) Interventions that use matrix metalloproteinases and immune-based mechanisms

9:45 AM - Edelle Field-Fote (Shepherd Center, Emory University) Functional restoration: the role of practice/training in neuroplasticity

10:10 AM - COFFEE BREAK

10:40 AM - FEATURED SPEAKER Marco Capogrosso (Univ. Pittsburgh) Spinal cord stimulation for the recovery of voluntary motor control: evidence for immediate and long-term effects

11:35 - Q&A Discussion with Panel

12:00 PM - LUNCH

1:00 PM - FEATURED SPEAKER Edgar T. (Terry) Walters (UT Houston)
Mechanisms of nociception and pain after CNS injury

SESSION III: AXON REGENERATION IN THE OPTIC NERVE

CHAIRPERSON Valeria Cavalli (Washington Univ. in St. Louis)

2:00 PM - Chair introduction and session overview

2:15 PM - Ava Udvadia (Univ. Milwaukee) In search of evolutionarily conserved mechanisms regulating successful optic nerve regeneration

2:45 PM - Larry Benowitz (Harvard Medical School/Boston Children’s Hospital) Optic nerve regeneration: Inflammatory mediators and transcriptional regulation

3:15 PM - Abigail Hackam (Bascom Palmer Eye Institute) Repurposing embryonic Wnt signaling pathways to promote optic nerve regeneration after injury

3:45 PM - Jeffrey Gross (UT Austin) Using zebrafish to identify neuroprotective and pro-regenerative genes and pathways active in retinal ganglion cells after optic nerve injury

4:15PM-4:45PM STRETCH BREAK

4:45-6:00 PM - DATA BLITZ I 5 minute slide presentations from presenters

6:00-8:00 PM - POSTER SESSION poster presentations (NOTE: We request that posters remain posted throughout the meeting to foster discussion. Poster Size should not exceed 48”x48”.)

8:00 PM - DINNER

Tuesday

April 25, 2023

SESSION IV: OPEN DATA SCIENCE

Chair introductions and session overview: Chair Maryann Martone (UCSD): Sponsored by ODC-SCI (8:20-8:30AM)

Each speaker will address how open data has impacted their science and its relevance to ISNR attendees

8:30 AM - Maryann Martone (UCSD)

8:55 AM - Aled Edward (UToronto)

9:20 AM - Adam Ferguson (UCSF)

9:45 AM - John Kramer (UBC)

10:15 AM - Karim Fouad (Univ. Alberta)

10:40 AM - COFFEE BREAK

11:00 AM - FEATURED SPEAKER Phil Popovich (The Ohio State Univ. Wexner Medical Center) Neuroimmune interactions after spinal cord injury

12:00 PM - LUNCH

1-4:30 PM - FREE TIME FOR SCIENTIFIC NETWORKING

1-1:45 PM - optional DEIJA workshop: PROMOTING DIVERSITY AT ISNR

4:30-5:30 PM - DATA BLITZ II

5:30-6:30 PM - HELLO MY NAME IS: TRAINEES MAKE 5 MIN INTROS OF THEIR RESEARCH TO FACULTY! When the music plays, the round ends!

6:30-7:30 PM - DINNER

SESSION V: Looking back to move forward

7:30-9 PM - FIRESIDE CHAT and COMMUNITY DISCUSSION

This session will provide trainees and members of the ISNR community an opportunity to pose questions to leaders in the field on their research and careers. Featured participants will share their experiences, insights, and advice on how to move the field forward.

Moderator: David Magnuson (Univ. Louisville)

Participants: Wolfram Tetzlaff (ICORD), Tessa Gordon (UToronto Sick Kids), Jacquie Bresnahan (UCSF), Os Steward (UC Irvine) and others.

April 26, 2023

Wednesday

SESSION VI: new investigators: new perspectives

8:15 AM - Meifan Chen (Univ. Kentucky) Intro and Session Overview

8:30 AM - Meifan Chen (Univ. Kentucky) Astrocytes in SCI injury and repair

8:45 AM - Andrea Tedeschi (The Ohio State University, Alt. Chairperson) Pericytes and SCI repair: focus on the promise and not the problem

9:00 AM - Jill Ward (Emory Univ. School of Medicine) Bio-luminescent optogenetic modulation of sympathetics for muscle metabolic health & recovery

9:15 AM - Abel Torres-Espin (UCSF) Applications of big data in SCI research

9:45 AM - Zin Khaing (Univ. Washington) Visualizing secondary damage after cervical SCI in real time and 3D, an opportunity to study neuroprotective interventions

10:00 AM - Faith Brennan (Queens University) Harnessing neuro-inflammation to improve SCI outcomes

10:15 AM - Brett Hilton (ICORD/UBC) An active priming machinery suppresses axon regeneration

10:30 AM - STRETCH BREAK

11:00 AM - FEATURED SPEAKER Matt Tresch (Northwestern Engineering): The role of the nervous system in controlling joint integrity

12:00 PM - LUNCH

1:00-4:15 PM - FREE TIME FOR SCIENTIFIC NETWORKING!

SESSION VII: EMERGING TOPICS and closing keynote

4:30 PM - FEATURED SPEAKER Julia Kaltschmidt (Stanford Univ.): Mapping the “second brain”: development and organization of the enteric nervous system (Emerging Topics)

5:30 PM - CLOSING KEYNOTE Robert Brownstone (UCL) What Does the Spinal Cord Do?

7:00 PM - SYMPOSIUM BANQUET AND AWARD PRESENTATIONS

April 27, 2023

THURSDAY

DEPARTURE